TSG101 anticorps (AA 340-370)

N° du produit ABIN3029403

Détail du produit anti-TSG101 anticorps

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Épitope: AA 340-370

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Purified

Immunogène: A portion of amino acids 340-370 from the human protein was used as the immunogen for this TSG101 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101 (TSG101 Produits)

Synonymes: anticorps CG9712, anticorps DmTSG101, anticorps Dmel\\CG9712, anticorps ESCRT-I, anticorps Tsg101, anticorps burs, anticorps dTSg101, anticorps dTsg101, anticorps dVps23, anticorps ept, anticorps tsg101, anticorps vps23, anticorps TSG101, anticorps MGC76193, anticorps TSG10, anticorps VPS23, anticorps AI255943, anticorps CC2, anticorps Rw, anticorps zgc:86926, anticorps tumor susceptibility 101, anticorps Tumor susceptibility gene 101, anticorps Tumor Susceptibility Gene homolog, anticorps tumor susceptibility gene 101, anticorps tumor susceptibility 101a, anticorps tumor susceptibility 101 L homeolog, anticorps TSG101, anticorps tsg-101, anticorps tsg101, anticorps Tsg101, anticorps tsg101a, anticorps tsg101.L

Sujet: TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

UniProt: Q99816