PLAU anticorps (AA 396-426)
Aperçu rapide pour PLAU anticorps (AA 396-426) (ABIN3032244)
Antigène
Voir toutes PLAU AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 396-426
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Purification
- Purified
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Immunogène
- A portion of amino acids 396-426 from the human protein was used as the immunogen for this UPA antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the UPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the UPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PLAU (Plasminogen Activator, Urokinase (PLAU))
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Autre désignation
- UPA
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Sujet
- PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
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UniProt
- P00749
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Antigène
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