Vitamin D Receptor anticorps (AA 274-299)

N° du produit ABIN3029599

Cet anticorps Lapin Polyclonal détecte spécifiquement Vitamin D Receptor dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour Vitamin D Receptor anticorps (AA 274-299) (ABIN3029599)

Antigène: Vitamin D Receptor (VDR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vitamin D Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Vitamin D Receptor anticorps

Épitope: AA 274-299

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 274-299 from the human protein was used as the immunogen for this VDR antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the VDR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the VDR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Vitamin D Receptor

Antigène: Vitamin D Receptor (VDR)

Autre désignation: VDR

Classe de substances: Chemical

Sujet: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway