WDR5 anticorps (C-Term)

N° du produit ABIN3029613

Détail du produit anti-WDR5 anticorps

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR5 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Rat, Bovine, Drosophila

Purification: Antigen affinity purified

Immunogène: This WDR5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the WDR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the WDR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur WDR5

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Autre désignation: WDR5 (WDR5 Produits)

Synonymes: anticorps BIG-3, anticorps SWD3, anticorps 2410008O07Rik, anticorps AA408785, anticorps AA960360, anticorps Big, anticorps Big-3, anticorps zgc:56591, anticorps zgc:76895, anticorps wu:fk47f04, anticorps wdr5-a, anticorps MGC80538, anticorps wdr5-b, anticorps MGC81485, anticorps big-3, anticorps swd3, anticorps xwdr5, anticorps WDR5B, anticorps WD repeat domain 5, anticorps WD repeat domain 5 L homeolog, anticorps WD repeat domain 5 S homeolog, anticorps WDR5, anticorps Wdr5, anticorps wdr5, anticorps wdr5.L, anticorps wdr5.S

Sujet: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

UniProt: P61964