WT1 anticorps (AA 346-375)

N° du produit ABIN3029622

Cet anticorps anti-WT1 est un anticorps Lapin Polyclonal détectant WT1 dans IHC, IF, FACS, WB et ELISA. Adapté pour Humain.

Aperçu rapide pour WT1 anticorps (AA 346-375) (ABIN3029622)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), ELISA

Détail du produit anti-WT1 anticorps

Épitope: AA 346-375

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Pig, Xenopus

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 346-375 from the human protein was used as the immunogen for this WT1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the WT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the WT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1 (Wilms Tumor Protein)

Sujet: Wilms Tumor protein is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].

UniProt: P19544

Pathways: Tube Formation