KRT20
Reactivité: Humain
WB, IHC, ICC, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Dilution for IHC: ready-to-use
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute with 1 mL deionized water
Buffer
PBS, pH 7.93
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Antigène
KRT20
(Keratin 20 (KRT20))
Autre désignation
keratin K20
Sujet
IT-Ks 20.10 represents an excellent marker for certain types of carcinomas such as adenocarcinomas of the colon, transitional cell carcinomas of the bladder and Merkel cell tumors of the skin. Very sensitive detection of intestestinal and gastric foveolar epithelium, urothelial umbrella cells, Merkel cells of epidermis as well as tumors originating therefrom (e.g. primary and metastatic colorectal carcinoma). Adenocarcinomas of breast, lung, endometrium and ovary (non-mucinous) as well as neuroendocrine tumors of the lung are essentially negative. Polypeptide recognized: protein IT (keratin K20, Mr 46 000, formerly also designated cytokeratin 20).
Poids moléculaire
Mr 180 000 polypeptide (clathrin heavy chain) from coated vesicles of various tissues