RANBP1 anticorps (N-Term)

N° du produit ABIN497936

L’anticorps anti-RANBP1 Polyclonal Lapin est utilisé pour la détection de RANBP1 dans des échantillons de Humain, Souris, Rat et Boeuf (Vache). Il a été validé pour WB et IF.

Aperçu rapide pour RANBP1 anticorps (N-Term) (ABIN497936)

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RANBP1 anticorps

Épitope: AA 1-187, N-Term

Specificité: Recognizes RAN binding protein 1/RANBP1 (1-187).

Réactivité croisée (Details): Species reactivity (expected):Rat (97 %), Bovine (88 %).
Species reactivity (tested):Human, Mouse.

Purification: Antigen-Affinity Chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 187 of Ran BP-1

Information d'application

Indications d'application: Suitable for use in Western blotting, and Immunocytochemistry/Immunofluorescence. Recommended Dilutions: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Positive Controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur RANBP1

Antigène: RANBP1 (RAN Binding Protein 1 (RANBP1))

Autre désignation: RANBP1

Sujet: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Synonyms: Ran-binding protein 1, Ran-specific GTPase-activating protein

ID gène: 5902, 9606

UniProt: P43487