POU3F3 anticorps (Internal Region)

N° du produit ABIN498034

Détail du produit anti-POU3F3 anticorps

Antigène: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp POU3F3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-HMLSHAHQWV TAL

Specificité: Recognizes POU3F3 / BRN1 / OCT8.

Réactivité croisée (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_006227.1. Genename: POU3F3

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 1-3 μg/mL. Approx 48 kDa band observed in Mouse and Rat Spinal Cordlysates (calculated MW of 50.8 kDa according to Human NP_006227.1 and 50.8 kDaaccording to Mouse NP_032926.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur POU3F3

Antigène: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Autre désignation: POU3F3 (POU3F3 Produits)

Synonymes: anticorps BRN1, anticorps OTF8, anticorps Brn1, anticorps RHS1, anticorps Brn-1, anticorps Otf8, anticorps Skin1, anticorps brn1, anticorps nrl-20, anticorps nrl20-A, anticorps pou1, anticorps pou23, anticorps wu:fb92g06, anticorps zfpou1, anticorps zp23, anticorps zp23pou, anticorps BRN-1.1, anticorps ZP12POU, anticorps brn1.1, anticorps pou12, anticorps wu:fc33a11, anticorps zp12, anticorps POU class 3 homeobox 3, anticorps POU domain, class 3, transcription factor 3, anticorps POU class 3 homeobox 3 S homeolog, anticorps POU class 3 homeobox 3b, anticorps POU class 3 homeobox 3a, anticorps POU3F3, anticorps Pou3f3, anticorps pou3f3.S, anticorps pou3f3b, anticorps pou3f3a

Sujet: POU3F3, also known as Brn1, is a member of the POU family of transcription factors that is predominantly expressed in the brain. It contains a characteristic POU domain and a homeobox DNA-binding domain. POU3F3 plays a role in the development of the brain and kidney by upregulating transcription of key genes in these tissues. For example, POU3F3 interacts with the proneural protein Mash1 and POU3F2 (Brn2) on the promoter of the Notch ligand Delta1 to activate Delta1 transcription, a key step in neurogenesis.Synonyms: BRN1, Brain-1, Brain-specific homeobox/POU domain protein 1, Brn-1, OTF-8, OTF8, Oct-8, Octamer-binding protein 8, Octamer-binding transcription factor 8, POU domain class 3 transcription factor 3

ID gène: 5455

NCBI Accession: NP_006227

UniProt: P20264