MON1A anticorps (Internal Region)

N° du produit ABIN498066

Détail du produit anti-MON1A anticorps

Antigène: MON1A (MON1 Homolog A (MON1A))

Épitope: AA 589-601, Internal Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp MON1A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-RPLKTIYYTG PNE

Specificité: This antibody is expected to recognize isoforms a and b (NP_115731.2, NP_001135973.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_115731.2, NP_001135973.1. Genename: MON1A

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/8000. Western blot: 1-3 μg/mL. Detects a band of Approx 50 kDa in lysates of cell line Jurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MON1A

Antigène: MON1A (MON1 Homolog A (MON1A))

Autre désignation: MON1A (MON1A Produits)

Synonymes: anticorps zgc:162873, anticorps 2810468K17Rik, anticorps RGD1308823, anticorps SAND1, anticorps MON1 homolog A, secretory trafficking associated, anticorps MON1 secretory trafficking family member A, anticorps MON1 homolog A, secretory traffciking associated, anticorps MON1A, anticorps mon1a, anticorps Mon1a

Sujet: MON1A also known as SAND1, is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene clusterand a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.Synonyms: SAND1, Vacuolar fusion protein MON1 homolog A

ID gène: 84315

NCBI Accession: NP_001135973

UniProt: Q86VX9

Pathways: Transition Metal Ion Homeostasis