HOXA4 anticorps (Internal Region)

N° du produit ABIN498071

L’anticorps Chèvre Polyclonal anti-HOXA4 a été validé pour WB et EIA. Il convient pour détecter HOXA4 dans des échantillons de Humain et Chien.

Aperçu rapide pour HOXA4 anticorps (Internal Region) (ABIN498071)

Antigène: HOXA4 (Homeobox A4 (HOXA4))

Reactivité: Humain, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXA4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-HOXA4 anticorps

Épitope: Internal Region

Séquence: C-QAKGPAHGLH ASH

Specificité: Recognizes HOXA4.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002132.3. Genename: HOXA4

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.1-0.3 μg/mL. Detects a band of Approx 36 kDa in Human Colon lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HOXA4

Antigène: HOXA4 (Homeobox A4 (HOXA4))

Autre désignation: HOXA4 / HOX1D

Sujet: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.Synonyms: Homeobox protein Hox-A4, Hox-1.4, Hox-1D

ID gène: 3201

NCBI Accession: NP_002132

UniProt: Q00056