HAT1 anticorps

N° du produit ABIN498132

Détail du produit anti-HAT1 anticorps

Antigène: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAT1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of HAT1 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur HAT1

Antigène: HAT1 (Histone Acetyltransferase 1 (HAT1))

Autre désignation: HAT1 (HAT1 Produits)

Synonymes: anticorps KAT1, anticorps HAC07, anticorps HAC7, anticorps HAG02, anticorps MIK19.19, anticorps MIK19_19, anticorps histone acetyltransferase of the GNAT family 2, anticorps hac106, anticorps hat1, anticorps zgc:92639, anticorps histone acetyltransferase 1, anticorps histone acetyltransferase of the GNAT family 2, anticorps histone acetyltransferase catalytic subunit, anticorps histone acetyltransferase Hat1, anticorps histone acetyltransferase 1 L homeolog, anticorps HAT1, anticorps Hat1, anticorps HAG2, anticorps hat1, anticorps hat1.L

Sujet: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.Synonyms: Histone acetyltransferase type B catalytic subunit

Poids moléculaire: approx. 49 kDa

ID gène: 8520

NCBI Accession: NP_003633

UniProt: O14929