HNRNPD/AUF1 anticorps
Aperçu rapide pour HNRNPD/AUF1 anticorps (ABIN498144)
Antigène
Voir toutes HNRNPD/AUF1 (HNRNPD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of hnRPD protein.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
-
Purification
- Affinity-chromatography using epitope-specific immunogen
-
-
-
-
Indications d'application
-
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
-
Autre désignation
- HnRNP-D0 / HNRNPD
-
Sujet
- HnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single stranded nonmonotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).Synonyms: AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D0
-
Poids moléculaire
- approx. 38 kDa
-
ID gène
- 3184
-
NCBI Accession
- NP_001003810
-
UniProt
- Q14103
Antigène
-