HNRNPD/AUF1 anticorps

N° du produit ABIN498144

Détail du produit anti-HNRNPD/AUF1 anticorps

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPD/AUF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of hnRPD protein.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity-chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HNRNPD/AUF1

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Autre désignation: HnRNP-D0 / HNRNPD (HNRNPD Produits)

Synonymes: anticorps AUF1, anticorps AUF1A, anticorps HNRPD, anticorps P37, anticorps hnRNPD0, anticorps Auf1, anticorps Hnrnpd, anticorps HNRNPD, anticorps p37, anticorps auf1a, anticorps hnrpd, anticorps hnrnpd0, anticorps C230004L04, anticorps Hnrpd, anticorps wu:fa28b06, anticorps zgc:162951, anticorps heterogeneous nuclear ribonucleoprotein D, anticorps heterogeneous nuclear ribonucleoprotein D L homeolog, anticorps HNRNPD, anticorps Hnrnpd, anticorps hnrnpd, anticorps hnrnpd.L

Sujet: HnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single stranded nonmonotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).Synonyms: AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D0

Poids moléculaire: approx. 38 kDa

ID gène: 3184

NCBI Accession: NP_001003810

UniProt: Q14103