KSR1 anticorps

N° du produit ABIN498178

Détail du produit anti-KSR1 anticorps

Antigène: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KSR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of KSR protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur KSR1

Antigène: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Autre désignation: Kinase Suppressor of Ras 1 (KSR1 Produits)

Synonymes: anticorps CG2899, anticorps Dmel\\CG2899, anticorps EK3-1, anticorps KSR, anticorps KSR-1, anticorps Ksr, anticorps Ksr-1, anticorps SR3-1, anticorps dKsr, anticorps l(3)j5E2, anticorps AW492498, anticorps B-KSR1, anticorps D11Bhm183e, anticorps D11Bhm184e, anticorps RSU2, anticorps hb, anticorps kinase suppressor of ras 1, anticorps kinase suppressor of ras, anticorps KSR1, anticorps ksr, anticorps Ksr1

Sujet: Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFβ-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFβ stimulation.Synonyms: KSR, KSR-1, KSR1

Poids moléculaire: approx. 115 kDa

ID gène: 8844

NCBI Accession: NP_055053

UniProt: Q8IVT5