MAF anticorps
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- Antigène Voir toutes MAF Anticorps
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAF est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous levels of c-Maf protein.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product MAF Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
- Autre désignation
- MAF (MAF Produits)
- Synonymes
- anticorps MAF, anticorps DKFZp459D1731, anticorps 2810401A20Rik, anticorps A230108G15Rik, anticorps AW047063, anticorps c-maf, anticorps CCA4, anticorps c-MAF, anticorps Maf2, anticorps cMaf, anticorps Z-cmaf, anticorps c-Maf, anticorps fl13d12, anticorps wu:fl13d12, anticorps C-Maf, anticorps MAF bZIP transcription factor, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian), anticorps avian musculoaponeurotic fibrosarcoma oncogene homolog, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a), anticorps MAF, anticorps Maf, anticorps mafa
- Sujet
- Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members Neural retina leucine zipper (Nrl), L-Maf, and Krml1/MafB (Maf-1) all bind to T-MARE sites and have been implicated in a wide variety of developmental and physiologic roles. The three small Maf family proteins (MafF, MafG, and MafK) are components of NF-E2 that function as heterodimers with the large tissuerestricted subunit of NF-E2 called p45, and they are implicated in the transcriptional regulation of many erythroid-specific genes. MafB is expressed in a wide variety of tissues and encodes a protein containing a typical bZip motif in its carboxy-terminal region. As a transcriptional activator, MafB plays a pivotal role in regulating lineage-specific gene expression during hematopoiesis by repressing Ets-1-mediated transcription of key erythroidspecific genes in myeloid cells.Synonyms: Proto-oncogene c-maf, Transcription factor Maf, V-maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog
- Poids moléculaire
- approx. 41 kDa
- ID gène
- 4094
- NCBI Accession
- NP_001026974
- UniProt
- O75444
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