SKIL anticorps
Aperçu rapide pour SKIL anticorps (ABIN498307)
Antigène
Voir toutes SKIL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of SnoN protein. (region surrounding Asp652)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography using epitope-specific immunogen
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Pureté
- > 95 % (by SDS-PAGE)
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Indications d'application
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SKIL (SKI-Like Oncogene (SKIL))
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Autre désignation
- SKIL / SnoN
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Sujet
- SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.Synonyms: SNO, Ski-like protein, Ski-related novel protein N, Ski-related oncogene, Ski-related protein, SnoA, Snol
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Poids moléculaire
- approx. 77 kDa
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ID gène
- 6498
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NCBI Accession
- NP_001138569
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UniProt
- P12757
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Antigène
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