RBMX anticorps

N° du produit ABIN498314

L’anticorps anti-RBMX Polyclonal Lapin est utilisé pour la détection de RBMX dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour RBMX anticorps (ABIN498314)

Antigène: RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBMX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RBMX anticorps

Specificité: This antibody detects endogenous levels of hnRNP G protein. (region surrounding Met40)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RBMX

Antigène: RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

Autre désignation: RBMX / HNRPG

Sujet: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. hnRNP G is a glycoprotein, which was originally identified as an autoantigen from German shepherd dogs with lupus-like syndrome. The gene encoding hnRNP G is located on chromosome Xq26 and is ubiquitously expressed. It contains one RNP-consensus RNA binding domain (RBD) and is related to RBMY, which is involved in spermatogenesis, and hnRNP G-T, which is a testis specific protein. All three proteins interact with Tra2b and therefore, are involved in pre-mRNA splicing.Synonyms: Glycoprotein p43, Heterogeneous nuclear ribonucleoprotein G, RBMXP1, RNA-binding motif protein X chromosome, hnRNP G

Poids moléculaire: approx. 40 kDa

ID gène: 27316

NCBI Accession: NP_002130

UniProt: P38159

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization