LI Cadherin anticorps

N° du produit ABIN498374

Détail du produit anti-LI Cadherin anticorps

Antigène: LI Cadherin

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LI Cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of LIcadherin protein. (region surrounding Thr363)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LI Cadherin

Antigène: LI Cadherin

Autre désignation: Cadherin-17 (LI Cadherin Produits)

Synonymes: anticorps CDH16, anticorps HPT-1, anticorps HPT1, anticorps HPT-1/LI, anticorps cb903, anticorps fb65d02, anticorps wu:fb65d02, anticorps cadherin-17, anticorps cadherin 17, anticorps cadherin 17, LI cadherin (liver-intestine), anticorps CDH17, anticorps Cdh17, anticorps cdh17

Sujet: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin

Poids moléculaire: approx. 90 kDa

ID gène: 1015

NCBI Accession: NP_001138135

UniProt: Q12864