MAPK15 anticorps

N° du produit ABIN498400

Détail du produit anti-MAPK15 anticorps

Antigène: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK15 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of ERK8 protein. (region surrounding Asp171)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS, pH 7.2, 0,05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MAPK15

Antigène: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Autre désignation: MAPK15 (MAPK15 Produits)

Synonymes: anticorps MGC138052, anticorps MGC99048, anticorps erk7, anticorps zgc:110345, anticorps ERK7, anticorps ERK8, anticorps BC048082, anticorps Erk7, anticorps ATMPK15, anticorps F25P22.9, anticorps F25P22_9, anticorps MAP kinase 15, anticorps mitogen-activated protein kinase 15, anticorps mitogen-activated protein kinase 15 L homeolog, anticorps MAP kinase 15, anticorps MAPK15, anticorps mapk15.L, anticorps mapk15, anticorps Tsp_00300, anticorps Mapk15, anticorps MPK15

Sujet: The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15

Poids moléculaire: approx. 60 kDa

ID gène: 225689

NCBI Accession: NP_620590

UniProt: Q8TD08