ZIC1 anticorps
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- Antigène Voir toutes ZIC1 Anticorps
- ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZIC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous levels of Zic1/2/3 protein. (region surrounding Asp348)
- Réactivité croisée (Details)
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Species reactivity (tested):Human, Mouse.
Also reacts to: ZIC2/3 - Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product ZIC1 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))
- Autre désignation
- ZIC1 (ZIC1 Produits)
- Synonymes
- anticorps ZIC, anticorps ZNF201, anticorps opl, anticorps Zic family member 1, anticorps Zic family member 1 S homeolog, anticorps zinc finger protein of the cerebellum 1, anticorps ZIC1, anticorps Zic1, anticorps zic1.S
- Sujet
- Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation, becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. The Zic1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family. Zic2 and Zic3 are highly similar genes. Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.Synonyms: ZIC, Zinc finger protein ZIC 1, Zinc finger protein of the cerebellum 1
- Poids moléculaire
- approx. 51 kDa
- ID gène
- 7545
- NCBI Accession
- NP_003403
- UniProt
- Q15915
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