LMX1B anticorps

N° du produit ABIN498413

Détail du produit anti-LMX1B anticorps

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMX1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of LMX1B protein. (region surrounding Asp159)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LMX1B

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Autre désignation: LMX1B (LMX1B Produits)

Synonymes: anticorps LMX1.2, anticorps NPS1, anticorps LMX, anticorps LMX1, anticorps LMX1.1, anticorps lmx1b, anticorps lmx1b.1, anticorps Xlmx1b, anticorps lmx1b.2, anticorps LIM homeobox transcription factor 1 beta, anticorps LIM homeobox transcription factor 1, beta b, anticorps LIM homeobox transcription factor 1, beta, gene 1 S homeolog, anticorps LIM homeobox transcription factor 1, beta a, anticorps LMX1B, anticorps Lmx1b, anticorps lmx1bb, anticorps lmx1b.1.S, anticorps lmx1ba

Sujet: The Lim class homeobox gene Lmx1b is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.Synonyms: LIM homeobox transcription factor 1-beta, LIM/homeobox protein 1.2, LIM/homeobox protein LMX1B, LMX-1.2, LMX1B

Poids moléculaire: approx. 42 kDa

ID gène: 4010

NCBI Accession: NP_002307

UniProt: O60663

Pathways: Dopaminergic Neurogenesis