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Cyclin O anticorps

CCNO Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN498417
  • Antigène Voir toutes Cyclin O (CCNO) Anticorps
    Cyclin O (CCNO)
    Reactivité
    • 23
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    • 1
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp Cyclin O est non-conjugé
    Application
    • 19
    • 18
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of UDG protein. (region surrounding His221)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Pureté
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product CCNO Anticorps primaire
  • Indications d'application
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Cyclin O (CCNO)
    Autre désignation
    Uracil-DNA Glycosylase 2 / Cyclin-O (CCNO Produits)
    Synonymes
    anticorps RGD1565217, anticorps ccnu, anticorps udg2, anticorps ung2, anticorps CCNU, anticorps MGC131111, anticorps C86987, anticorps Ccnu, anticorps E130318K11, anticorps Ung2, anticorps UDG2, anticorps cyclin O, anticorps cyclin O L homeolog, anticorps Ccno, anticorps ccno, anticorps CCNO, anticorps ccno.L
    Sujet
    The human UNG-gene encodes nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-DNA glycosylase using differentially regulated promoters, PA and PB, and alternative splicing to produce two proteins with unique N-terminal sorting sequences. Uracil in DNA may result from deamination of cytosine which can give rise to transition mutations. Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA. This is probably a biologically important function in the prevention of mutagenesis resulting from cytosine deamination. UNG2 removes misincorporated dUMP residues.Synonyms: CCNO, Cyclin-like uracil-DNA glycosylase, UDG2, UNG2
    Poids moléculaire
    approx. 35 kDa
    ID gène
    10309
    NCBI Accession
    NP_066970
    UniProt
    P22674
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