AKAP1 anticorps

N° du produit ABIN498433

Détail du produit anti-AKAP1 anticorps

Antigène: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of AKAP149 protein. (region surrounding asn306)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity-Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AKAP1

Antigène: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Autre désignation: AKAP1 (AKAP1 Produits)

Synonymes: anticorps AKAP1, anticorps akap1, anticorps fa08b04, anticorps wu:fa08b04, anticorps AKAP, anticorps AKAP121, anticorps AKAP149, anticorps AKAP84, anticorps D-AKAP1, anticorps PPP1R43, anticorps PRKA1, anticorps SAKAP84, anticorps TDRD17, anticorps Akap, anticorps C76494, anticorps C81186, anticorps DAKAP1, anticorps S-AKAP84, anticorps Akap84, anticorps A-kinase anchoring protein 1, anticorps A kinase (PRKA) anchor protein 1b, anticorps A kinase (PRKA) anchor protein 1, anticorps AKAP1, anticorps akap1b, anticorps akap1, anticorps Akap1

Sujet: The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses.Synonyms: A kinase anchor protein 1 mitochondrial, A-kinase anchor protein 149 kDa, AKAP-1, AKAP149, Dual specificity A-kinase-anchoring protein 1, PRKA1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein 84

Poids moléculaire: approx. 90 kDa

ID gène: 8165

NCBI Accession: NP_003479

UniProt: Q92667

Pathways: Synaptic Membrane