GAL4 anticorps
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- Antigène Voir toutes GAL4 (LGALS4) Anticorps
- GAL4 (LGALS4) (Galectin 4 (LGALS4))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GAL4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of Galectin-4 protein. (region surrounding Lys83)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product LGALS4 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GAL4 (LGALS4) (Galectin 4 (LGALS4))
- Autre désignation
- Galectin-4 (LGALS4 Produits)
- Synonymes
- anticorps LGALS4, anticorps gal4, anticorps l36lbp, anticorps MGC86186, anticorps galectin-4, anticorps xgalectin-VIa, anticorps gal-4, anticorps L36LBP, anticorps L-36, anticorps L36LBI, anticorps GAL4, anticorps galectin 4, anticorps lectin, galactoside-binding, soluble, 4 L homeolog, anticorps Galectin-4, anticorps lectin, galactose binding, soluble 4, anticorps LGALS4, anticorps lgals4.L, anticorps leg4, anticorps Lgals4
- Sujet
- Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-4, also known as Gal-4, L36 or LGALS4 maps to human chromosome 19q13.13 and encodes a 36-37 kDa protein. The Galectin-4 protein is composed of 323 amino acids and contains two homologous carbohydrate recognition domains (CRD) and all amino acids typically conserved in the galectin family. Expression of Galectin-4 correlates with the malignant potential of human hepatocellular carcinoma (HCC) and is differentially regulated depending on cell-cell contact, serum growth factors, cell growth and cell differentiation status. Galectin-4 expression is detected in epithelial cells of the colon, rectum, intestine, and in HT29 and LS174T cell lines. Galectin-4 is underexpressed in colorectal cancer and is preferentially upregulated in cells prone to peritoneal dissemination.Synonyms: Antigen NY-CO-27, Galectin4, L-36 lactose-binding protein, L36LBP, LGALS4, Lactose-binding lectin 4
- Poids moléculaire
- approx. 36 kDa
- ID gène
- 3960
- NCBI Accession
- NP_006140
- UniProt
- P56470
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