DEFA4 anticorps

N° du produit ABIN498518

L’anticorps anti-DEFA4 Polyclonal Lapin est utilisé pour la détection de DEFA4 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour DEFA4 anticorps (ABIN498518)

Antigène: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEFA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DEFA4 anticorps

Specificité: This antibody detects endogenous levels of Defensin α4 protein. (region surrounding Asp27)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur DEFA4

Antigène: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Autre désignation: Defensin alpha 4

Sujet: Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteri,a fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.Synonyms: DEF4, DEFA4, HNP-4, HP-4, Neutrophil defensin 4

Poids moléculaire: approx. 11 kDa

ID gène: 1669

NCBI Accession: NP_001916

UniProt: P12838