alpha Defensin 1 anticorps

N° du produit ABIN498525

Détail du produit anti-alpha Defensin 1 anticorps

Antigène: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Defensin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Defensin α1 protein. (region surrounding Ser52)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur alpha Defensin 1

Antigène: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Autre désignation: Defensin alpha 1 (DEFA1 Produits)

Synonymes: anticorps DEF1, anticorps DEFA2, anticorps HNP-1, anticorps HP-1, anticorps HP1, anticorps MRS, anticorps Defcr, anticorps Defcr1, anticorps DEFA1, anticorps Defa, anticorps Def, anticorps GB19392, anticorps defensin alpha 1, anticorps defensin, alpha 1, anticorps defensin alpha 5, anticorps alpha-defensin 1A, anticorps defensin 1, anticorps neutrophil defensin 1, anticorps DEFA1, anticorps Defa1, anticorps Defa5, anticorps MNP1A, anticorps Def1, anticorps LOC107973256

Sujet: β-Defensins (also designated BD, and HBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. β-defensins are involved in the resistance of epithelial surfaces, such as airway surface fluid, to microbial colonization. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Human β-defensin 1, isolated from the kidney, has a molecular mass of 3.9 kDa. Human β-defensin 1 shares homology with other β-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, β-defensin 1 may play a role in the mucosal defenses of the lung.Synonyms: DEF1, DEFA1, DEFA2, HNP-1, MRS, Neutrophil defensin 1

ID gène: 1667

NCBI Accession: NP_001035965

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin