NPY anticorps
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- Antigène Voir toutes NPY Anticorps
- NPY (Neuropeptide Y (NPY))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NPY est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of NPY protein. (region surrounding Pro94)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NPY Anticorps primaire
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- Indications d'application
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- NPY (Neuropeptide Y (NPY))
- Autre désignation
- Neuropeptide Y / NPY (NPY Produits)
- Synonymes
- anticorps 0710005A05Rik, anticorps PYY4, anticorps NPY02, anticorps RATNPY, anticorps RATNPY02, anticorps si:dkey-22m8.5, anticorps npy, anticorps npyb, anticorps preproNPY, anticorps pyy4, anticorps xnpy, anticorps npya, anticorps MGC86288, anticorps prepronpy, anticorps NPY, anticorps NPY1, anticorps neuropeptide Y, anticorps neuropeptide Y S homeolog, anticorps neuropeptide Y L homeolog, anticorps Npy, anticorps NPY, anticorps npy, anticorps npy.S, anticorps npy.L, anticorps LOC100533423
- Sujet
- A gene located on chromosome 7p15.1 encodes a 36-amino acid protein designated NPY (Neuropeptide Y). NPY consists of a polyproline stretch followed by an amphipathic alphahelix. NPY shares a 50 % amino acid homology with pancreatic polypeptide gene (PP). The NPY hormone family consists of NPY, PP and peptide YY. NPY is expressed throughout the central and peripheral nervous system, particularly in the deep layers of the cortex and smaller cell bodies in the white matter. NPY interacts with the Y-receptor family of G-protein coupled receptors. NPY interacts with NPY receptor Y1 to increase corticotropin levels and decrease noradrenaline levels in the hypothalamus. Through interactions in the hypothalus, NPY plays important roles in the regulation of energy balance by stimulating food intake. NPY favors energy storage by increasing lipoprotein lipase activity in white adipose tissue. A leucine(7)-to- proline(7) polymorphism has been implicated in an increase in alcohol preference, and decrease in cholesterol metabolism.
- Poids moléculaire
- approx. 11 kDa
- ID gène
- 4852
- NCBI Accession
- NP_000896
- UniProt
- P01303
- Pathways
- Feeding Behaviour
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