IL32 anticorps
Aperçu rapide pour IL32 anticorps (ABIN498668)
Antigène
Voir toutes IL32 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of IL-32 protein. (region surrounding Lys226)
-
Réactivité croisée (Details)
- Species reactivity (tested):Human.
-
Purification
- Affinity chromatography
-
Pureté
- > 95 % by SDS-PAGE
-
-
-
-
Indications d'application
-
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1,0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- IL32 (Interleukin 32 (IL32))
-
Autre désignation
- Interleukin-32 / IL32
-
Sujet
- The interleukins make up a large family of well characterized cytokines, primarily of hematopoietic cell origin. The interleukins are secreted by immune cells (mainly macrophages, B cells and T cells) that regulate a wide range of immune system functions. Interleukin-32 (IL-32), also designated Natural Killer (NK) cell transcript 4 (nk4), may play a role in inflammatory responses such as lymphocyte activation. IL-32 is secreted following stimulation with inflammatory cytokines such as IL-1beta and IFN-gamma, and by NK cells after exposure to IL-12 and IL-18. It also induces production of IL-1beta, TNFalpha, MIP-2 and IL-6. Expression of IL-32 increases after activation of T cells by mitogens or activation of NK cells by IL-2. The IL-32 protein contains three potential Nmyristoylation sites, a tyrosine sulfation site, an RGD cellattachment sequence and multiple putative phosphorylation sites. Human IL-32 exists as four isoforms.Synonyms: IL-32, NK4, Natural killer cells protein 4, TAIF, Tumor necrosis factor alpha-inducing factor
-
Poids moléculaire
- approx. 27 kDa
-
ID gène
- 9235
-
NCBI Accession
- NP_001012649
-
UniProt
- P24001
Antigène
-