PGC anticorps
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- Antigène Voir toutes PGC Anticorps
- PGC (Pepsinogen C (PGC))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PGC est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of Pepsin C protein. (region surrounding Phe306)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product PGC Anticorps primaire
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- Indications d'application
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PGC (Pepsinogen C (PGC))
- Autre désignation
- Pepsinogen Group II (PGC Produits)
- Synonymes
- anticorps PEPC, anticorps PGII, anticorps 2210410L06Rik, anticorps Upg-1, anticorps Upg1, anticorps CPGC, anticorps gastricsin, anticorps PG1, anticorps Pg-1, anticorps PGNC, anticorps PGC, anticorps Gastricsin, anticorps progastricsin (pepsinogen C), anticorps progastricsin, anticorps PGC, anticorps Pgc
- Sujet
- Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, Pepsinogen, by removal of a 41 amino acid segment from the amino end. Pepsinogen is synthesized in the stomach lining, hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for Pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. It shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of Pepsinogen and Pepsin, especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.Synonyms: Gastricsin, PGC, Pepsinogen C, Progastricsin
- Poids moléculaire
- approx. 42 kDa
- ID gène
- 5225
- NCBI Accession
- NP_002621
- UniProt
- P20142
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