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SNAIL anticorps (pSer246)
SNAI1
Reactivité: Humain, Souris
WB, IF, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-SNAIL anticorps
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Antigène
Voir toutes SNAIL (SNAI1) Anticorps
SNAIL (SNAI1)
Épitope
Tous les épitopes à travers SNAIL Anticorps.
pSer246
Reactivité
Toutes les réactivités sur SNAIL Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur SNAIL Anticorps
Lapin
Clonalité
Toutes les clonalités sur SNAIL Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SNAIL Anticorps
Cet anticorp SNAIL est non-conjugé
Application
Tous les applications à travers SNAIL Anticorps.
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody detects endogenous levels of p-SNAI 1 protein, only when phosphorylated at Ser246.
Réactivité croisée (Details)
Species reactivity (tested):Human, Mouse.
Purification
Affinity chromatography
Pureté
> 95 % by SDS-PAGE
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Information d'application
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Indications d'application
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur SNAIL
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Antigène
SNAIL (SNAI1)
Autre désignation
SNAI1 (SNAI1 Produits )
Synonymes
anticorps SLUGH2, anticorps SNA, anticorps SNAH, anticorps SNAIL, anticorps SNAIL1, anticorps dJ710H13.1, anticorps AI194338, anticorps Sna, anticorps Sna1, anticorps Snail, anticorps Snail1, anticorps SNAI1, anticorps BG:DS01845.1, anticorps CG3956, anticorps Dmel\\CG3956, anticorps Sco, anticorps br28, anticorps br29, anticorps l(2)35Db, anticorps l(2)br28, anticorps l(2)br29, anticorps l(3)br28, anticorps l35Db, anticorps sn, anticorps Xsnail, anticorps sna, anticorps snail1, anticorps xSna, anticorps Snai, anticorps sna2, anticorps snail2, anticorps cb643, anticorps sna-1, anticorps sna1, anticorps snai1, anticorps snail1a, anticorps zgc:109820, anticorps snail family transcriptional repressor 1, anticorps snail family zinc finger 1, anticorps snail homolog 1 (Drosophila), anticorps snail, anticorps zinc-finger transcription factor Snail, anticorps snail family zinc finger 1 S homeolog, anticorps protein escargot, anticorps transcription factor protein, anticorps snail zinc finger protein, anticorps snail family zinc finger 1b, anticorps snail family zinc finger 1a, anticorps SNAI1, anticorps Snai1, anticorps sna, anticorps snail, anticorps snai1.S, anticorps LOC410464, anticorps snai1b, anticorps snai1a
Sujet
The SNAIL family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of DrosophilaSNAIL,and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna,each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development.Synonyms: Protein snail homolog 1, SNAH, Zinc finger protein SNAI1
Poids moléculaire
approx. 29 kDa
ID gène
6615
NCBI Accession
NP_005976
UniProt
O95863
Pathways
Negative Regulation of intrinsic apoptotic Signaling
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