CLDN8 anticorps
Aperçu rapide pour CLDN8 anticorps (ABIN499047)
Antigène
Voir toutes CLDN8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of Claudin-8 protein. (region surrounding Ile118)
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography
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Pureté
- > 95 % by SDS-PAGE
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Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CLDN8 (Claudin 8 (CLDN8))
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Autre désignation
- Claudin-8 / CLDN8
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Sujet
- Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-8 is a multi-pass membrane protein that belongs to the claudin family. Localized to the caput and the lateral margins of principal cells, claudin-8 plays an important role in tight junction-specific obliteration of the intercellular space.Synonyms: PRO1573, UNQ779
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Poids moléculaire
- approx. 28 kDa
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ID gène
- 9073
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NCBI Accession
- NP_955360
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UniProt
- P56748
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Pathways
- Hepatitis C
Antigène
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