C1QBP anticorps

N° du produit ABIN499052

L’anticorps anti-C1QBP Polyclonal Lapin est utilisé pour la détection de C1QBP dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour C1QBP anticorps (ABIN499052)

Antigène: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1QBP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-C1QBP anticorps

Specificité: This antibody detects endogenous levels of C1QBP protein. (region surrounding Lys100)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C1QBP

Antigène: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Autre désignation: C1QBP

Sujet: The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system (SCS). The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway), carbohydrate (the lectin pathway) or bacterial (alternative pathway) initiation. C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1 (hyaluronanbinding protein 1), is known to bind the globular heads of C1q molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, coagulation and kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF.Synonyms: Complement component 1 Q subcomponent-binding protein, GC1QBP, GC1q-R protein, GC1q-R protein, Glycoprotein gC1qBP, HABP1, Hyaluronan-binding protein 1, Mitochondrial matrix protein p32, SF2P32, p32, p33, p33

Poids moléculaire: approx. 32 kDa

ID gène: 708

NCBI Accession: NP_001203

UniProt: Q07021

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly