FBLN3 anticorps
Aperçu rapide pour FBLN3 anticorps (ABIN499069)
Antigène
Voir toutes FBLN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of Fibulin-3 protein. (region surrounding Pro150)
-
Réactivité croisée (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography using epitope-specific immunogen
-
Pureté
- > 95 % (by SDS-PAGE)
-
-
-
-
Indications d'application
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- FBLN3 (Fibulin 3 (FBLN3))
-
Autre désignation
- Fibulin-3
-
Sujet
- Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.Synonyms: DHRD, DRAD, EFEMP1, EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, FBLN3, FBNL, Fibrillin-like protein, Fibulin 3, MLVT, MTLV, S1-5
-
Poids moléculaire
- approx. 55 kDa
-
ID gène
- 2202
-
NCBI Accession
- NP_001034437
-
UniProt
- Q12805
-
Pathways
- EGFR Signaling Pathway
Antigène
-