GABRD anticorps

N° du produit ABIN499074

Détail du produit anti-GABRD anticorps

Antigène: GABRD (GABA A Receptor delta (GABRD))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRD est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of GABAA Rδ protein. (region surrounding Asp181)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur GABRD

Antigène: GABRD (GABA A Receptor delta (GABRD))

Autre désignation: GABRD (GABRD Produits)

Synonymes: anticorps GABRD, anticorps EIG10, anticorps EJM7, anticorps GEFSP5, anticorps GABAA-RD, anticorps AI853201, anticorps gamma-aminobutyric acid type A receptor delta subunit, anticorps gamma-aminobutyric acid (GABA) A receptor, subunit delta, anticorps GABRD, anticorps Gabrd

Sujet: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (γ-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rrho1 and GABAA Rrho2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.Synonyms: GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta

Poids moléculaire: approx. 51 kDa

ID gène: 2563

NCBI Accession: NP_000806

UniProt: O14764