TSTA3 anticorps

N° du produit ABIN499078

Cet anticorps Lapin Polyclonal détecte spécifiquement TSTA3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSTA3 anticorps (ABIN499078)

Antigène: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSTA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TSTA3 anticorps

Specificité: This antibody detects endogenous levels of FX protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TSTA3

Antigène: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Autre désignation: TSTA3

Sujet: GDP-L-fucose synthetase (FX protein), also designated Tissue-specific transplantation antigen P35B or GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, belongs to the fucose synthetase family. FX is a red cell NADP(H)- binding protein that is important in leukocyte adhesion and trafficking processes. The FX protein, together with GDP-mannose 4,6-dehydratase, can convert GDP-mannose to GDP-L-fucose by catalyzing the two-step epimerase and reductase reactions. GDP-L-fucose is the substrate of several fucosyltransferases that function in the expression of many glycoconjugates such as blood group ABH antigens and developmental adhesion antigens. Defects in the gene encoding for the FX protein cause leukocyte adhesion deficiency (LAD).Synonyms: 5-epimerase-4-reductase, GDP-4-keto-6-deoxy-D-mannose-3, GDP-L-fucose synthetase, Protein FX, Red cell NADP(H)-binding protein, SDR4E1, Short chain dehydrogenase/reductase family 4E member 1

Poids moléculaire: approx. 40 kDa

ID gène: 7264

NCBI Accession: NP_003304

UniProt: Q13630