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HOXB2 anticorps (Homeobox B2) Primary Antibody

HOXB2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499088
$513.70
Plus shipping costs $45.00
0.1 mg
local_shipping Destination: Etats-Unis
Available
  • Antigène
    HOXB2
    Reactivité
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 16
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    Cet anticorp HOXB2 est non-conjugé
    Application
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody detects endogenous levels of HoxB2 protein. (region surrounding Pro67)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography using epitope-specific immunogen
    Pureté
    > 95 % (by SDS-PAGE)
  • Indications d'application
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    HOXB2
    Autre désignation
    HOXB2 / HOX2H (HOXB2 Antibody Extrait)
    Synonymes
    hox2, hox2h, hox-2.8, Hoxb-2, Z-151, hoxb2, hm:zehn0229, HOX2, HOX2H, Hox-2.8, K8, AI894218, Hoxbes2, homeobox B2, homeobox B2a, homeobox protein Hox-B2, HOXB2, hoxb2, hoxb2a, LOC733446, Hoxb2
    Sujet
    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.Synonyms: Homeobox protein Hox-B2, Hox-2.8, Hox-2H, K8
    Poids moléculaire
    approx. 38 kDa
    ID gène
    3212
    NCBI Accession
    NP_002136
    UniProt
    P14652
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