Cet anticorps anti-MRPS36 Polyclonal Lapin (ABIN499092) détecte spécifiquement MRPS36 dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
Western blot: 1: 500 - 1: 1000. Immunohistocemistry on paraffin sections: 1: 50 - 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Antigène
MRPS36
(Mitochondrial Ribosomal Protein S36 (MRPS36))
Autre désignation
MRPS36
Sujet
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S36 (mitochondrial ribosomal protein S36), is a 103 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-S36 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Synonyms: 28S ribosomal protein S36, DC47, S36mt, mitochondrial