MDFI anticorps

N° du produit ABIN499093

Cet anticorps Lapin Polyclonal détecte spécifiquement MDFI dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MDFI anticorps (ABIN499093)

Antigène: MDFI (MyoD Family Inhibitor (MDFI))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDFI est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MDFI anticorps

Specificité: This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MDFI

Antigène: MDFI (MyoD Family Inhibitor (MDFI))

Autre désignation: MDFI

Sujet: MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor

Poids moléculaire: approx. 25 kDa

ID gène: 4188

NCBI Accession: NP_005577

UniProt: Q99750

Pathways: Maintenance of Protein Location