MDFI anticorps
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- Antigène Voir toutes MDFI Anticorps
- MDFI (MyoD Family Inhibitor (MDFI))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MDFI est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product MDFI Anticorps primaire
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- Indications d'application
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MDFI (MyoD Family Inhibitor (MDFI))
- Autre désignation
- MDFI (MDFI Produits)
- Synonymes
- anticorps MDFI, anticorps I-MF, anticorps I-mfa, anticorps I-mf, anticorps RGD1560271, anticorps MyoD family inhibitor, anticorps MDFI, anticorps Mdfi
- Sujet
- MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor
- Poids moléculaire
- approx. 25 kDa
- ID gène
- 4188
- NCBI Accession
- NP_005577
- UniProt
- Q99750
- Pathways
- Maintenance of Protein Location
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