TIAL1 anticorps (Internal Region)

N° du produit ABIN499121

Détail du produit anti-TIAL1 anticorps

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Épitope: Internal Region

Reactivité: Humain, Souris, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-SPEITTEDIK SAFAP

Specificité: This antibody is expected to recognize both isoforms (NP_003243.1, NP_001029097.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the Internal region of Human TIAL1 (NP_003243.1 and NP_001029097.1) Genename: TIAL1

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/64000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line K562.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TIAL1

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Autre désignation: TIAL1 (TIAL1 Produits)

Synonymes: anticorps TCBP, anticorps TIAR, anticorps 5330433G13Rik, anticorps AL033329, anticorps mTIAR, anticorps zgc:66130, anticorps tcbp, anticorps tiar, anticorps TIA1 cytotoxic granule associated RNA binding protein like 1, anticorps Tia1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIA1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIAL1, anticorps Tial1, anticorps tial1

Sujet: TIA1 is a member of an RNA binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.Synonyms: Nucleolysin TIAR, TIA-1-related protein

Poids moléculaire: 43.4 kDa (NP_001029097.1)

ID gène: 7073

NCBI Accession: NP_003243

UniProt: Q01085