HOXA1 anticorps

N° du produit ABIN499123

Cet anticorps Chèvre Polyclonal détecte spécifiquement HOXA1 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien et Porc.

Aperçu rapide pour HOXA1 anticorps (ABIN499123)

Antigène: HOXA1 (Homeobox A1 (HOXA1))

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXA1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-HOXA1 anticorps

Specificité: This antibody is expected to recognize reported isoforms a and b (NP_005513.1 and, NP_705873.2).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Détails sur HOXA1

Antigène: HOXA1 (Homeobox A1 (HOXA1))

Autre désignation: HOXA1 / HOX1F

Sujet: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-1F, Homeobox protein Hox-A1

ID gène: 3198

NCBI Accession: NP_005513

UniProt: P49639

Pathways: Sensory Perception of Sound