Anoctamin 5 anticorps (C-Term)

N° du produit ABIN499159

Cet anticorps Lapin Polyclonal détecte spécifiquement Anoctamin 5 dans WB et EIA. Il présente une réactivité envers Souris et Humain.

Aperçu rapide pour Anoctamin 5 anticorps (C-Term) (ABIN499159)

Antigène: Anoctamin 5 (ANO5)

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anoctamin 5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Anoctamin 5 anticorps

Épitope: AA 798-828, C-Term

Specificité: Recognizes ANO5 (C-term).

Purification: Protein A Chromatography followed by peptide affinity purification

Immunogène: Synthetic peptide -KLH conjugated between 798~828 amino acids from the C-terminal region of Human ANO5. Genename: ANO5

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Anoctamin 5

Antigène: Anoctamin 5 (ANO5)

Autre désignation: ANO5

Sujet: ANO5 is a member of the anoctamin family of transmembrane proteins. This protein is likely a calcium activated chloride channel. Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD), also known as osteogenesis imperfecta with unusual skeletal lesions or gnathodiaphyseal sclerosis. GDD is a rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood, however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity.Synonyms: Anoctamin-5, GDD1, Gnathodiaphyseal dysplasia 1 protein, TMEM16E, Transmembrane 16E

ID gène: 203859

NCBI Accession: NP_001136121

UniProt: Q75V66