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XPNPEP1 anticorps (C-Term)

L’anticorps Chèvre Polyclonal anti-XPNPEP1 a été validé pour WB. Il convient pour détecter XPNPEP1 dans des échantillons de Humain, Souris, Rat, Porc, Chien et Boeuf (Vache).
N° du produit ABIN499169

Aperçu rapide pour XPNPEP1 anticorps (C-Term) (ABIN499169)

Antigène

Voir toutes XPNPEP1 Anticorps
XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

Reactivité

Humain, Souris, Rat, Porc, Chien, Boeuf (Vache)

Hôte

  • 20
  • 7
  • 1
Chèvre

Clonalité

  • 21
  • 7
Polyclonal

Conjugué

  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp XPNPEP1 est non-conjugé

Application

  • 16
  • 15
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 6
    • 4
    • 1
    • 1
    C-Term

    Séquence

    C-LIRETQPISK QH

    Specificité

    This antibody detects XPNPEP1 at C-term. It is expected to recognize isoform 1 and 2 (NP_065116.2, NP_001161076.1).

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse, rat, cow, pigSpecies reactivity (tested):Human

    Purification

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    Immunogène

    Peptide from the C Terminus of the protein sequence according to NP_065116.2, NP_001161076.1
  • Indications d'application

    Peptide ELISA: limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in Human Heart, Skeletal Muscleand Pancreas lysates (calculated MW of 69.0 kDa according to NP_065116.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
  • Antigène

    XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

    Autre désignation

    XPNPEP1

    Sujet

    XPNPEP1 is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. As a result of its specificity toward proline, it has been suggested that XPNPEP1 is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of XPNPEP1 results in excretion of large amounts of imino-oligopeptides in urine.Synonyms: Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1 soluble, XPNPEPL, XPNPEPL1, Xaa-Pro aminopeptidase 1

    ID gène

    7511

    NCBI Accession

    NP_065116

    UniProt

    Q9NQW7
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