Serotonin Receptor 3B anticorps (Internal Region)

N° du produit ABIN499176

Détail du produit anti-Serotonin Receptor 3B anticorps

Antigène: Serotonin Receptor 3B (HTR3B)

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 3B est non-conjugé

Application: Western Blotting (WB)

Séquence: C-SNYLQTQDQT DQQE

Specificité: This antibody detects Serotonin receptor 3B (Internal).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region (near C-terminus) of the protein sequence according to NP_006019.1

Information d'application

Indications d'application: Peptide ELISA: 1: 16000 (limit dilution). Western blot: 1-3 μg/mL. Approx 51 kDa band observed in Human Brain (Cerebral Cortex,Hippocampus and Amygdala) lysates (calculated MW of 50.1 kDa according toNP_006019.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Détails sur Serotonin Receptor 3B

Antigène: Serotonin Receptor 3B (HTR3B)

Abstract: HTR3B Produits

Synonymes: anticorps HTR3B, anticorps 5-HT3B, anticorps 5-hydroxytryptamine receptor 3B, anticorps 5-hydroxytryptamine (serotonin) receptor 3B, anticorps HTR3B, anticorps Htr3b

Sujet: There are 4 main groups of receptors which bind the neurotransmitter serotonin: 5HT1, 5HT2 5HT3 and 5HT4. 5HT3B receptor is subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin). This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Through interactions with these receptors, serotonin is able to exert a wide variety of physiological functions. 5HT3 receptors are cation-selective transmitter-gated ion channels. 5HT3B receptor mutations have been implicated in depression.Synonyms: 5-HT3-B, 5-HT3B, 5-hydroxytryptamine receptor 3B

ID gène: 9177

NCBI Accession: NP_006019

UniProt: O95264

Pathways: Synaptic Membrane