Akirin 1 anticorps (N-Term)

N° du produit ABIN499253

Détail du produit anti-Akirin 1 anticorps

Antigène: Akirin 1 (AKIRIN1)

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Akirin 1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to AKIRIN1.

Purification: Affinity chromatography purified via peptide column

Immunogène: Akirin1 antibody was raised against a 16 amino acid peptide near the amino terminus of the human Akirin1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: Akirin1 antibody can be used for detection of Akirin1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Akirin 1

Antigène: Akirin 1 (AKIRIN1)

Autre désignation: AKIRIN1 (AKIRIN1 Produits)

Synonymes: anticorps C1orf108, anticorps RP11-781D11.2, anticorps STRF2, anticorps 6330407G11Rik, anticorps wu:fa96c11, anticorps wu:fc08a11, anticorps zgc:64050, anticorps AKIRIN1, anticorps strf2, anticorps akirin 1, anticorps akirin 1 S homeolog, anticorps akirin-1 pseudogene, anticorps AKIRIN1, anticorps Akirin1, anticorps akirin1, anticorps akirin1.S, anticorps LOC100316864, anticorps LOC100356339

Sujet: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.Synonyms: Akirin-1, C1orf108

ID gène: 79647

UniProt: Q9H9L7