ALDH5A1 anticorps (C-Term)
Aperçu rapide pour ALDH5A1 anticorps (C-Term) (ABIN499267)
Antigène
Voir toutes ALDH5A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody reacts to ALDH5A1.
-
Purification
- Affinity chromatography purified via peptide column
-
Immunogène
- Aldh5A1 antibody was raised against a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
ELISA. Western Blot: Aldh5A1 antibody can be used for detection of Aldh5A1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS containing 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
-
-
- ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))
-
Autre désignation
- ALDH5A1 / SSADH
-
Sujet
- Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial
-
ID gène
- 7915
-
NCBI Accession
- NP_733936
-
UniProt
- P51649
-
Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
-