APC1 anticorps (C-Term)

N° du produit ABIN499291

Détail du produit anti-APC1 anticorps

Antigène: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: APC1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human APC1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: APC1 antibody can be used for detection of APC1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur APC1

Antigène: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Autre désignation: APC1 / ANAPC1 (ANAPC1 Produits)

Synonymes: anticorps APC1, anticorps MCPR, anticorps TSG24, anticorps DDBDRAFT_0186456, anticorps DDBDRAFT_0234263, anticorps DDB_0186456, anticorps DDB_0234263, anticorps 2610021O03Rik, anticorps AI047775, anticorps AI853536, anticorps AW547281, anticorps Apc1, anticorps Mcpr, anticorps tsg24, anticorps EMBRYO DEFECTIVE 2771, anticorps MOP10.10, anticorps MOP10_10, anticorps anaphase promoting complex subunit 1, anticorps E3 ubiquitin ligase, anticorps ANAPC1, anticorps Anapc1, anticorps CC1G_09696, anticorps anapc1, anticorps EMB2771

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein

ID gène: 64682

UniProt: Q9H1A4