CDC27 anticorps (C-Term)
Aperçu rapide pour CDC27 anticorps (C-Term) (ABIN499295)
Antigène
Voir toutes CDC27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- APC3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APC3.
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Isotype
- IgG
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Indications d'application
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ELISA. Western Blot: APC3 antibody can be used for detection of APC3 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))
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Autre désignation
- CDC27
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Sujet
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC3, also known as CDC27, a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), is a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. APC3 contains a tetratricopeptide repeat (TPR) region and interacts with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1.Synonyms: CDC27Hs, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H-NUC
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ID gène
- 996
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NCBI Accession
- NP_001247
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UniProt
- P30260
Antigène
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