ANAPC7 anticorps (C-Term)

N° du produit ABIN499303

Cet anticorps Lapin Polyclonal détecte spécifiquement ANAPC7 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ANAPC7 anticorps (C-Term) (ABIN499303)

Antigène: ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ANAPC7 anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: APC7 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APC7.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: APC7 antibody can be used for detection of APC7 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ANAPC7

Antigène: ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))

Autre désignation: APC7 / ANAPC7

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.Synonyms: Anaphase-promoting complex subunit 7, Cyclosome subunit 7

ID gène: 51434

NCBI Accession: NP_057322

UniProt: Q4KMX6