NOL3 anticorps (N-Term)

N° du produit ABIN499329

Cet anticorps anti-NOL3 est un anticorps Lapin Polyclonal détectant NOL3 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NOL3 anticorps (N-Term) (ABIN499329)

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOL3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-NOL3 anticorps

Épitope: N-Term

Specificité: ARC antibody was raised against a peptide corresponding to amino acids 2 to 18 of human origin. These sequences are identical to those of human nuclear protein Nop30 (2) and differ from those of the rat homolog of ARC by one amino acid (3).

Purification: Affinity chromatography purified via peptide column

Immunogène: Human ARC (N-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: ARC antibody can be used for detection of ARC at 1/500 dilution. Whole celllysate from HeLa cells can be used as positive control and an approximately 25 kDa bandcan be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur NOL3

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Autre désignation: NOL3 / ARC

Sujet: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue (1).Synonyms: Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, NOP, Nop30, Nucleolar protein 3, Nucleolar protein of 30 kDa

ID gène: 8996

NCBI Accession: NP_003937

UniProt: O60936