NOL3 anticorps (N-Term)
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- Antigène Voir toutes NOL3 Anticorps
- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOL3 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- ARC antibody was raised against a peptide corresponding to amino acids 2 to 18 of human origin. These sequences are identical to those of human nuclear protein Nop30 (2) and differ from those of the rat homolog of ARC by one amino acid (3).
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Human ARC (N-Terminus) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product NOL3 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: ARC antibody can be used for detection of ARC at 1/500 dilution. Whole celllysate from HeLa cells can be used as positive control and an approximately 25 kDa bandcan be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
- Autre désignation
- NOL3 / ARC (NOL3 Produits)
- Synonymes
- anticorps ARC, anticorps FCM, anticorps MYP, anticorps NOP, anticorps NOP30, anticorps B430311C09Rik, anticorps MYC, anticorps Nop30, anticorps Arc, anticorps nucleolar protein 3, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps NOL3, anticorps Nol3
- Sujet
- Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue (1).Synonyms: Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, NOP, Nop30, Nucleolar protein 3, Nucleolar protein of 30 kDa
- ID gène
- 8996
- NCBI Accession
- NP_003937
- UniProt
- O60936
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