ARL6IP1 anticorps (C-Term)

N° du produit ABIN499337

L’anticorps Lapin Polyclonal anti-ARL6IP1 a été validé pour WB, EIA et IHC (p). Il convient pour détecter ARL6IP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour ARL6IP1 anticorps (C-Term) (ABIN499337)

Antigène: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6IP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ARL6IP1 anticorps

Épitope: C-Term

Specificité: ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.

Purification: Ion exchange chromatography

Immunogène: Human ARMER / ARL6IP / AIP1 (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: ARMER antibody can be used for detection of ARMER at 0.5 to 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur ARL6IP1

Antigène: ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))

Autre désignation: ARL6IP1

Sujet: Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12 (2), other caspases such as caspase-9 are also thought to be activated following ER stress (3). Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, KIAA0069

ID gène: 23204

UniProt: Q15041